Newly discovered info on L234

Here is what I read today about L234 in HIV (the book, 2000). L234 is in the NNRTI binding pocket which is in the palm domain of p66 (roughly 10-15 angstroms away from the catalytic site (containing the aspartate residues). The NNRTI binding pocket is lipophilic and consists of three stranded beta sheets (beta 4, 7 and 8). What is of interest to me is the fact that eventhough L234 is indeed part of the wall of the binding pocket, its mutation has not been freqently associated with NNRTI resistance (except for the case of capravi???, which i wrote about awhile ago). Furthermore, it is associated with our inhibitor. But i guess i will learn more about that after the conference in L.A.